TAP Binding Protein (Tapasin) (TAPBP) Peptide
TAPBP
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN938605
Quick Overview for TAP Binding Protein (Tapasin) (TAPBP) Peptide (ABIN938605)
Target
TAPBP
(TAP Binding Protein (Tapasin) (TAPBP))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- GEAPPELLCL VSHFYPSGGL EVEWELRGGP GGRSQKAEGQ RWLSALRHHS
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of TAPBP antibody,
Alternative Names: TAPBP control peptide, TAPBP antibody Blocking Peptide, Anti-TAPBP Blocking Peptide, Tap Binding Protein Blocking Peptide, Tapasin Blocking Peptide, NGS17 Blocking Peptide, TAPA Blocking Peptide, TPN Blocking Peptide, TPSN Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- TAPBP (TAP Binding Protein (Tapasin) (TAPBP))
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Background
- TAPBP is a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum.
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Molecular Weight
- 46 kDa
Target
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