Gephyrin (GPHN) Peptide
GPHN
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Quick Overview for Gephyrin (GPHN) Peptide (ABIN938629)
Target
Gephyrin (GPHN)
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- GEQPTQTVMP GQVMRVTTGA PIPCGADAVV QVEDTELIRE SDDGTEELEV
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of GPHN antibody,
Alternative Names: Gephyrin control peptide, Gephyrin antibody Blocking Peptide, Anti-Gephyrin Blocking Peptide, GPHN Blocking Peptide, GEPH Blocking Peptide, GPH Blocking Peptide, GPHRYN Blocking Peptide, KIAA1385 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- Gephyrin (GPHN)
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Background
- GPHN is a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described, however, the full-length nature of all transcript variants is not currently known.
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Molecular Weight
- 80 kDa
Target
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