Centromere Protein B (CENPB) Peptide
CENPB
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN938663
Quick Overview for Centromere Protein B (CENPB) Peptide (ABIN938663)
Target
CENPB
(Centromere Protein B (CENPB))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- GGEDSDSDSE EEDDEEEDDE DEDDDDDEED GDEVPVPSFG EAMAYFAMVK
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of CENPB antibody,
Alternative Names: CENPB control peptide, CENPB antibody Blocking Peptide, Anti-CENPB Blocking Peptide, Centromere Protein B 80Kda Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- CENPB (Centromere Protein B (CENPB))
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Background
- CENPB is a highly conserved protein that facilitates centromere formation. It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family. It contains a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognised by sera from patients with anti-centromere antibodies.
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Molecular Weight
- 65 kDa
Target
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