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Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) Peptide

CASP4 Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN938719

Quick Overview for Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) Peptide (ABIN938719)

Target

Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))

Origin

Mammalian

Source

  • 8
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Peptide Type

    Synthetic

    Sequence

    GILEGICGTV HDEKKPDVLL YDTIFQIFNN RNCLSLKDKP KVIIVQACRG

    Characteristics

    A synthetic peptide for use as a blocking control in assays to test for specificity of CASP4 antibody,
    Alternative Names: CASP4 control peptide, CASP4 antibody Blocking Peptide, Anti-CASP4 Blocking Peptide, caspase 4, apoptosis-related cysteine peptidase Blocking Peptide, ICE(rel)II Blocking Peptide, ICEREL-II Blocking Peptide, ICH-2 Blocking Peptide, Mih1/TX Blocking Peptide, TX Blocking Peptide, CASP4, CASP-4, CASP 4, CASP-4 Blocking Peptide, CASP 4 Blocking Peptide
  • Application Notes

    Optimal conditions should be determined by the investigator

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Handling Advice

    Avoid repeated freeze/thaw cycles.

    Storage

    -20 °C

    Storage Comment

    Store at -20 °C long term.
  • Target

    Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))

    Background

    This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.

    Molecular Weight

    10 kDa
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