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Cathepsin E (CTSE) Peptide

CTSE Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN938721
  • Target See all Cathepsin E (CTSE) products
    Cathepsin E (CTSE)
    Peptide Type
    Synthetic
    Origin
    Mammalian
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    GILGLGYPSL AVGGVTPVFD NMMAQNLVDL PMFSVYMSSN PEGGAGSELI
    Characteristics
    A synthetic peptide for use as a blocking control in assays to test for specificity of CTSE antibody,
    Alternative Names: CTSE control peptide, CTSE antibody Blocking Peptide, Anti-CTSE Blocking Peptide, cathepsin E Blocking Peptide, CATE Blocking Peptide
  • Application Notes
    Optimal conditions should be determined by the investigator
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C long term.
  • Target
    Cathepsin E (CTSE)
    Background
    The protein encoded by this gene is a gastric aspartyl protease that functions as a disulfide-linked homodimer. This protease, which is a member of the peptidase C1 family, has a specificity similar to that of pepsin A and cathepsin D. It is an intracellular proteinase that does not appear to be involved in the digestion of dietary protein and is found in highest concentration in the surface of epithelial mucus-producing cells of the stomach. It is the first aspartic proteinase expressed in the fetal stomach and is found in more than half of gastric cancers. It appears, therefore, to be an oncofetal antigen. Transcript variants utilizing alternative polyadenylation signals and two transcript variants encoding different isoforms exist for this gene.
    Molecular Weight
    40 kDa
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