TGFB-Induced Factor Homeobox 1 (TGIF1) Peptide
TGIF1
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN938892
Quick Overview for TGFB-Induced Factor Homeobox 1 (TGIF1) Peptide (ABIN938892)
Target
TGIF1
(TGFB-Induced Factor Homeobox 1 (TGIF1))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- GQNTDIQQIA AKNFTDTSLM YPEDTCKSGP STNTQSGLFN TPPPTPPDLN
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of TGIF1 antibody,
Alternative Names: TGIF1 control peptide, TGIF1 antibody Blocking Peptide, Anti-TGIF1 Blocking Peptide, Tgfb-Induced Factor Homeobox 1 Blocking Peptide, HPE4 Blocking Peptide, MGC39747 Blocking Peptide, MGC5066 Blocking Peptide, TGIF Blocking Peptide, TGIF1, TGIF-1, TGIF 1, TGIF-1 Blocking Peptide, TGIF 1 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))
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Background
- TGIF1 is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain.
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Molecular Weight
- 43 kDa
Target
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