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TGIF1 Products

(TGFB-Induced Factor Homeobox 1 (TGIF1))

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The protein encoded by this gene is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain. Alternative splicing has been observed at this locus and eight variants, encoding four distinct isoforms, are described. [provided by RefSeq, Jul 2008].

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Featured TGIF1 Categories

TGIF1 Antibodies

High quality antibodies with extensive validation data.

TGIF1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TGIF1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7155852
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF, ICC
Validations
  • (3)
Cat. No. ABIN6265552
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB
Validations
  • (2)
Cat. No. ABIN655999
Quantity 400 μL
Datasheet Datasheet

Recommended TGIF1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1322619
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1322621
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3120949
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our TGIF1 products

Pertile, Schäche, Islam, Chen, Dirani, Mitchell, Baird: "Assessment of TGIF as a candidate gene for myopia." in: Investigative ophthalmology & visual science, Vol. 49, Issue 1, pp. 49-54, (2008) (PubMed).

Ferrand, Demange, Prunier, Seo, Atfi: "A mechanism for mutational inactivation of the homeodomain protein TGIF in holoprosencephaly." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 21, Issue 2, pp. 488-96, (2007) (PubMed).

Chavarría-Siles, Walss-Bass, Quezada, Dassori, Contreras, Medina, Ramírez, Armas, Salazar, Leach, Raventos, Escamilla: "TGFB-induced factor (TGIF): a candidate gene for psychosis on chromosome 18p." in: Molecular psychiatry, Vol. 12, Issue 11, pp. 1033-41, (2007) (PubMed).

Synonyms and alternative names related to TGIF1

TGFB induced factor homeobox 1 (TGIF1), TGFB-induced factor homeobox 1 (Tgif1), TGFB-induced factor homeobox 1 (tgif1), TGFB induced factor homeobox 1 (tgif1), TGFB induced factor homeobox 1 S homeolog (tgif1.S), AA959811, AI462167, fa06h05, fb33g11, HPE4, hpe4, Tfig, TGIF, Tgif, tgif, tgif1, wu:fa06h05, wu:fb33g11, zgc:55852

Protein level used designations for TGIF1

  • 5'-TG-3'-interacting factor 1
  • TALE homeobox TG-interacting factor
  • homeobox protein TGIF1
  • transforming growth factor-beta-induced factor
  • TALE family homeobox
  • TG interacting factor 1
  • TG interacting factor
  • TGFB-induced factor (TALE family homeobox)
  • avian knotted-related protein
  • homeobox protein AKR
  • homeodomain protein AKR
  • TG-interacting factor
  • TGFB-induced factor homeobox 1
  • TG-interacting homeobox protein
  • TGFB induced factor homeobox 1 S homeolog
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