Signal Transducer and Activator of Transcription 5B (STAT5B) Peptide
STAT5B
Reactivity: Mammalian
Host: Synthetic
BP, IHC, WB
Catalog No. ABIN938936
Quick Overview for Signal Transducer and Activator of Transcription 5B (STAT5B) Peptide (ABIN938936)
Target
STAT5B
(Signal Transducer and Activator of Transcription 5B (STAT5B))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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Peptide Type
- Synthetic
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Sequence
- GSATYMDQAP SPAVCPQAHY NMYPQNPDSV LDTDGDFDLE DTMDVARRVE
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of STAT5 B antibody,
Alternative Names: STAT5B control peptide, STAT5B antibody Blocking Peptide, Anti-STAT5B Blocking Peptide, signal transducer and activator of transcription 5B Blocking Peptide, STAT5 Blocking Peptide, STAT5B, STATB-5, STATB 5, STATB-5 Blocking Peptide, STATB 5 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- STAT5B (Signal Transducer and Activator of Transcription 5B (STAT5B))
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Background
- STAT5B is a member of the STAT family of transcription factors. In response to cytokines andgrowth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT5B mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression.
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Molecular Weight
- 90 kDa
Target
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