Coagulation Factor VIII (F8) Peptide
F8
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN938955
$398.38
Plus shipping costs $50.00
100 μg
Shipping to:
United States
Delivery in 16 to 22 Business Days
Quick Overview for Coagulation Factor VIII (F8) Peptide (ABIN938955)
Target
Factor VIII (F8)
(Coagulation Factor VIII (F8))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- GSKGEKGERG RAGELGEAGP SGEPGVPGDA GMPGERGEAG HRGSAGALGP
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of F8 antibody,
Alternative Names: F8 control peptide, F8 antibody Blocking Peptide, Anti-F8 Blocking Peptide, coagulation factor VIII, procoagulant component Blocking Peptide, AHF Blocking Peptide, DXS1253E Blocking Peptide, F8B Blocking Peptide, F8C Blocking Peptide, FVIII Blocking Peptide, HEMA Blocking Peptide, F8, F-8, F 8, F-8 Blocking Peptide, F 8 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- Factor VIII (F8) (Coagulation Factor VIII (F8))
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Background
- This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation, factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.
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Molecular Weight
- 63 kDa
Target
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