Methylmalonic Aciduria (Cobalamin Deficiency) CblD Type, with Homocystinuria (MMADHC) Peptide
Quick Overview for Methylmalonic Aciduria (Cobalamin Deficiency) CblD Type, with Homocystinuria (MMADHC) Peptide (ABIN938972)
Target
Origin
Source
Application
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Peptide Type
- Synthetic
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Sequence
- GSSGSDESHV AAAPPDICSR TVWPDETMGP FGPQDQRFQL PGNIGFDCHL
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of C2 orf25 antibody,
Alternative Names: C2orf25 control peptide, C2orf25 antibody Blocking Peptide, Anti-C2orf25 Blocking Peptide, Methylmalonic Aciduria Blocking Peptide, Cobalamin Deficiency Cbld Type With Homocystinuria Blocking Peptide, CL25022 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- MMADHC (Methylmalonic Aciduria (Cobalamin Deficiency) CblD Type, with Homocystinuria (MMADHC))
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Background
- Vitamin B12 (cobalamin) is an essential cofactor in several metabolic pathways. Intracellular conversion of cobalamin to adenosylcobalamin in mitochondria and to methylcobalamin in cytoplasm is necessary for homeostasis of methylmalonic acid and homocysteine. C2ORF25 encodes a protein involved in an early step of cobalamin metabolism.
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Molecular Weight
- 33 kDa
Target
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