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Interleukin 10 Receptor, alpha (IL10RA) Peptide

IL10RA Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN938981
  • Target See all IL-10RA (IL10RA) products
    IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))
    Peptide Type
    Synthetic
    Origin
    Mammalian
    Source
    • 2
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    GSVNLEIHNG FILGKIQLPR PKMAPANDTY ESIFSHFREY EIAIRKVPGN
    Characteristics
    A synthetic peptide for use as a blocking control in assays to test for specificity of IL10 RA antibody,
    Alternative Names: IL10R Alpha control peptide, IL10R Alpha antibody Blocking Peptide, Anti-IL10R Alpha Blocking Peptide, Interleukin 10 Receptor Alpha Blocking Peptide, CDW210A Blocking Peptide, HIL-10R Blocking Peptide, IL-10R1 Blocking Peptide, IL10R Blocking Peptide, IL10RA Blocking Peptide, IL10, IL-10, IL 10, IL-10 Blocking Peptide, IL 10 Blocking Peptide
  • Application Notes
    Optimal conditions should be determined by the investigator
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C long term.
  • Target
    IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))
    Background
    IL10RA is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases.
    Molecular Weight
    61 kDa
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