Interleukin 10 Receptor, alpha (IL10RA) Peptide
IL10RA
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN938981
Quick Overview for Interleukin 10 Receptor, alpha (IL10RA) Peptide (ABIN938981)
Target
IL-10RA (IL10RA)
(Interleukin 10 Receptor, alpha (IL10RA))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- GSVNLEIHNG FILGKIQLPR PKMAPANDTY ESIFSHFREY EIAIRKVPGN
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of IL10 RA antibody,
Alternative Names: IL10R Alpha control peptide, IL10R Alpha antibody Blocking Peptide, Anti-IL10R Alpha Blocking Peptide, Interleukin 10 Receptor Alpha Blocking Peptide, CDW210A Blocking Peptide, HIL-10R Blocking Peptide, IL-10R1 Blocking Peptide, IL10R Blocking Peptide, IL10RA Blocking Peptide, IL10, IL-10, IL 10, IL-10 Blocking Peptide, IL 10 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))
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Background
- IL10RA is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases.
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Molecular Weight
- 61 kDa
Target
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