Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4) Peptide
CACNB4
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN939035
$517.90
Plus shipping costs $50.00
100 μg
Shipping to:
United States
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Quick Overview for Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4) Peptide (ABIN939035)
Target
CACNB4
(Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- GVPDPGTGAS SGTRTPDVKA FLESPWSLDP ASASPEPVPH ILASSRQWDP
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of CACNB4 antibody,
Alternative Names: CACNB4 control peptide, CACNB4 antibody Blocking Peptide, Anti-CACNB4 Blocking Peptide, Calcium Channel Voltage-Dependent Beta 4 Subunit Blocking Peptide, CACNB4, CACNB-4, CACNB 4, CACNB-4 Blocking Peptide, CACNB 4 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- CACNB4 (Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4))
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Background
- CACNB4 is a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. CACNB4 plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE) and juvenile myoclonic epilepsy (JME).
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Molecular Weight
- 50 kDa
Target
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