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Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4) Peptide

CACNB4 Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN939035
  • Target See all CACNB4 products
    CACNB4 (Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4))
    Peptide Type
    Synthetic
    Origin
    Mammalian
    Source
    • 6
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    GVPDPGTGAS SGTRTPDVKA FLESPWSLDP ASASPEPVPH ILASSRQWDP
    Characteristics
    A synthetic peptide for use as a blocking control in assays to test for specificity of CACNB4 antibody,
    Alternative Names: CACNB4 control peptide, CACNB4 antibody Blocking Peptide, Anti-CACNB4 Blocking Peptide, Calcium Channel Voltage-Dependent Beta 4 Subunit Blocking Peptide, CACNB4, CACNB-4, CACNB 4, CACNB-4 Blocking Peptide, CACNB 4 Blocking Peptide
  • Application Notes
    Optimal conditions should be determined by the investigator
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C long term.
  • Target
    CACNB4 (Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4))
    Synonyms
    CAB4 Peptide, CACNLB4 Peptide, EA5 Peptide, EIG9 Peptide, EJM Peptide, EJM4 Peptide, EJM6 Peptide, 3110038O15Rik Peptide, Cchb4 Peptide, lethargic Peptide, lh Peptide, CACNB4 Peptide, cacnb4.2 Peptide, calcium voltage-gated channel auxiliary subunit beta 4 Peptide, calcium channel, voltage-dependent, beta 4 subunit Peptide, calcium channel, voltage-dependent, beta 4a subunit Peptide, CACNB4 Peptide, Cacnb4 Peptide, cacnb4.1 Peptide, cacnb4 Peptide, cacnb4a Peptide
    Background
    CACNB4 is a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. CACNB4 plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE) and juvenile myoclonic epilepsy (JME).
    Molecular Weight
    50 kDa
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