Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (SMG8) Peptide
SMG8
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
-
- Target See all SMG8 products
- SMG8 (Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (SMG8))
- Peptide Type
- Synthetic
- Origin
- Mammalian
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- HCVHKFHSLP KSGEKPEADR NPPVLYHNSR ARSTGACNCG RKQAPRDDPF
- Characteristics
-
A synthetic peptide for use as a blocking control in assays to test for specificity of C17 orf71 antibody,
Alternative Names: C17ORF71 control peptide, C17ORF71 antibody Blocking Peptide, Anti-C17ORF71 Blocking Peptide, FLJ10587 Blocking Peptide
-
-
- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
-
- Target
- SMG8 (Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (SMG8))
- Background
- The C17ORF71 protein is a component of the SMG1C complex, a mRNA surveillance complex that recognises and degrades mRNAs containing premature translation termination codons (PTCs) via the nonsense-mediated mRNA decay (NMD). The complex probably acts by associating with ribosomes during tranlation termination on mRNPs. If an exon junction complex (EJC) is located 50-55 or more nucleotides downstream from the termination codon, SMG1 phosphorylates UPF1/RENT1, triggering nonsense-mediated mRNA decay (NMD).
- Molecular Weight
- 110 kDa
-
You are here:
