Pyruvate Kinase M2 (PKM2) Peptide
PKM2
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN939172
Quick Overview for Pyruvate Kinase M2 (PKM2) Peptide (ABIN939172)
Target
PKM2
(Pyruvate Kinase M2 (PKM2))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- HLQLFEELRR LAPITSDPTE ATAVGAVEAS FKCCSGAIIV LTKSGRSAHQ
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of PKM2 antibody,
Alternative Names: PKM2 control peptide, PKM2 antibody Blocking Peptide, Anti-PKM2 Blocking Peptide, pyruvate kinase, muscle Blocking Peptide, CTHBP Blocking Peptide, MGC3932 Blocking Peptide, OIP3 Blocking Peptide, PK3 Blocking Peptide, PKM Blocking Peptide, TCB Blocking Peptide, THBP1 Blocking Peptide, PKM2, PKM-2, PKM 2, PKM-2 Blocking Peptide, PKM 2 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- PKM2 (Pyruvate Kinase M2 (PKM2))
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Background
- This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.
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Molecular Weight
- 58 kDa
Target
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