Pre-mRNA Branch Site Protein p14 (SF3B14) Peptide
Quick Overview for Pre-mRNA Branch Site Protein p14 (SF3B14) Peptide (ABIN939174)
Target
Origin
Source
Application
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Peptide Type
- Synthetic
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Sequence
- HLSGFNVCNR YLVVLYYNAN RAFQKMDTKK KEEQLKLLKE KYGINTDPPK
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of SF3 B14 antibody,
Alternative Names: SF3B14 control peptide, SF3B14 antibody Blocking Peptide, Anti-SF3B14 Blocking Peptide, Splicing Factor 3B 14 Kda Subunit Blocking Peptide, CGI-110 Blocking Peptide, HSPC175 Blocking Peptide, Ht006 Blocking Peptide, P14 Blocking Peptide, SAP14 Blocking Peptide, SF3B14a Blocking Peptide, SF3B14, SFB14-3, SFB14 3, SFB14-3 Blocking Peptide, SFB14 3 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- Pre-mRNA Branch Site Protein p14 (SF3B14)
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Background
- SF3B14 is a 14 kDa protein subunit of the splicing factor 3b complex. Splicing factor 3b associates with both the U2 and U11/U12 small nuclear ribonucleoprotein complexes (U2 snRNP) of spliceosomes. This 14 kDa protein interacts directly with subunit 1 of the splicing factor 3b complex. SF3B14 also interacts directly with the adenosine that carries out the first transesterification step of splicing at the pre-mRNA branch site.
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Molecular Weight
- 14 kDa
Target
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