Lysine (K)-Specific Demethylase 6B (Kdm6b) Peptide
Kdm6b
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN939220
Quick Overview for Lysine (K)-Specific Demethylase 6B (Kdm6b) Peptide (ABIN939220)
Target
Kdm6b
(Lysine (K)-Specific Demethylase 6B (Kdm6b))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- HRAVDPPGAR AAREAFALGG LSCAGAWSSC PPHPPPRSAW LPGGRCSASI
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of JMJD3 antibody,
Alternative Names: JMJD3 control peptide, JMJD3 antibody Blocking Peptide, Anti-JMJD3 Blocking Peptide, jumonji domain containing 3, histone lysine demethylase Blocking Peptide, KIAA0346 Blocking Peptide, JMJD3, JMJD-3, JMJD 3, JMJD-3 Blocking Peptide, JMJD 3 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- Kdm6b (Lysine (K)-Specific Demethylase 6B (Kdm6b))
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Background
- JMJD3 is a histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. It plays a central role in regulation of posterior development, by regulating HOX gene expression. It is involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation.
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Molecular Weight
- 181 kDa
Target
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