serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1) Peptide
SPTLC1
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN939291
Quick Overview for serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1) Peptide (ABIN939291)
Target
SPTLC1
(serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- ICPLPELVKL KYKYKARIFL EESLSFGVLG EHGRGVTEHY GINIDDIDLI
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of SPTLC1 antibody,
Alternative Names: SPTLC1 control peptide, SPTLC1 antibody Blocking Peptide, Anti-SPTLC1 Blocking Peptide, Serine Palmitoyltransferase Long Chain Base Subunit 1 Blocking Peptide, HSAN Blocking Peptide, HSAN1 Blocking Peptide, HSN1 Blocking Peptide, LBC1 Blocking Peptide, LCB1 Blocking Peptide, MGC14645 Blocking Peptide, SPT1 Blocking Peptide, SPTI Blocking Peptide, SPTLC1, SPTLC-1, SPTLC 1, SPTLC-1 Blocking Peptide, SPTLC 1 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- SPTLC1 (serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))
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Background
- Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor. SPTLC1 is the long chain base subunit 1 of serine palmitoyltransferase. Mutations in SPTLC1 gene were identified in patients with hereditary sensory neuropathy type 1.
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Molecular Weight
- 53 kDa
Target
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