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Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 2 (KCNN2) Peptide

KCNN2 Reactivity: Mammalian Host: Synthetic BP, IHC, WB
Catalog No. ABIN939300
  • Target See all KCNN2 products
    KCNN2 (Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 2 (KCNN2))
    Peptide Type
    Synthetic
    Origin
    Mammalian
    Source
    • 6
    Synthetic
    Application
    Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
    Sequence
    IDHAKVRKHQ RKFLQAIHQL RSVKMEQRKL NDQANTLVDL AKTQNIMYDM
    Characteristics
    A synthetic peptide for use as a blocking control in assays to test for specificity of KCNN2 antibody,
    Alternative Names: KCNN2 control peptide, KCNN2 antibody Blocking Peptide, Anti-KCNN2 Blocking Peptide, Potassium Intermediate/Small Conductance Calcium-Activated Channel Subfamily N Member 2 Blocking Peptide, KCNN2, KCNN-2, KCNN 2, KCNN-2 Blocking Peptide, KCNN 2 Blocking Peptide
  • Application Notes
    Optimal conditions should be determined by the investigator
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C long term.
  • Target
    KCNN2 (Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 2 (KCNN2))
    Background
    Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by KCNN2 is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. KCNN2 is a member of the KCNN family of potassium channel genes.
    Molecular Weight
    64 kDa
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