Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B) Peptide
POLR3B
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN939329
Quick Overview for Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B) Peptide (ABIN939329)
Target
POLR3B
(Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- IEKVMISSNA EDAFLIKMLL RQTRRPEIGD KFSSRHGQKG VCGLIVPQED
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of POLR3 B antibody,
Alternative Names: POLR3B control peptide, POLR3B antibody Blocking Peptide, Anti-POLR3B Blocking Peptide, RNA Polymerase IIIB Blocking Peptide, FLJ10388 Blocking Peptide, RPC2 Blocking Peptide, POLR3B, POLRB-3, POLRB 3, POLRB-3 Blocking Peptide, POLRB 3 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- POLR3B (Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B))
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Background
- POLR3B belongs to the RNA polymerase beta chain family. DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. POLR3B is the second largest core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. It is proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol III is composed of mobile elements and RPC2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft.
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Molecular Weight
- 128 kDa
Target
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