AU RNA Binding Protein/enoyl-CoA Hydratase (AUH) Peptide
AUH
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN939360
Quick Overview for AU RNA Binding Protein/enoyl-CoA Hydratase (AUH) Peptide (ABIN939360)
Target
AUH
(AU RNA Binding Protein/enoyl-CoA Hydratase (AUH))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- IGMSLAKELI FSARVLDGKE AKAVGLISHV LEQNQEGDAA YRKALDLARE
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of AUH antibody,
Alternative Names: AUH control peptide, AUH antibody Blocking Peptide, Anti-AUH Blocking Peptide, Au Rna Binding Protein/Enoyl-Coenzyme A Hydratase Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- AUH (AU RNA Binding Protein/enoyl-CoA Hydratase (AUH))
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Background
- AU-specific RNA-binding enoyl-CoA hydratase (AUH) protein binds to the AU-rich element (ARE), a common element found in the 3' UTR of rapidly decaying mRNA such as c-fos, c-myc and granulocyte/ macrophage colony stimulating factor. ARE elements are involved in directing RNA to rapid degradation and deadenylation. AUH is also homologous to enol-CoA hydratase, an enzyme involved in fatty acid degradation, and has been shown to have intrinsic hydratase enzymatic activity. AUH is thus a bifunctional chimera between RNA binding and metabolic enzyme activity.
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Molecular Weight
- 37 kDa
Target
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