Recombination Activating Gene 1 (RAG1) Peptide
RAG1
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN939380
Quick Overview for Recombination Activating Gene 1 (RAG1) Peptide (ABIN939380)
Target
RAG1
(Recombination Activating Gene 1 (RAG1))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- IIERDGSIGA WASEGNESGN KLFRRFRKMN ARQSKCYEME DVLKHHWLYT
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of Rag1 antibody,
Alternative Names: Rag1 control peptide, Rag1 antibody Blocking Peptide, Anti-Rag1 Blocking Peptide, recombination activating gene 1 Blocking Peptide, Rag-1 Blocking Peptide, Rag1, Rag-1, Rag 1, Rag-1 Blocking Peptide, Rag 1 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- RAG1 (Recombination Activating Gene 1 (RAG1))
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Background
- As a catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment. RAG2 is not a catalytic component but is required for all known catalytic activities.
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Molecular Weight
- 119 kDa
Target
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