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Solute Carrier Organic Anion Transporter Family, Member 1B1 (SLCO1B1) Peptide

SLCO1B1 Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN939387

Quick Overview for Solute Carrier Organic Anion Transporter Family, Member 1B1 (SLCO1B1) Peptide (ABIN939387)

Target

SLCO1B1 (Solute Carrier Organic Anion Transporter Family, Member 1B1 (SLCO1B1))

Origin

Mammalian

Source

  • 2
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Peptide Type

    Synthetic

    Sequence

    IILIYAMKKK YQEKDINASE NGSVMDEANL ESLNKNKHFV PSAGADSETH

    Characteristics

    A synthetic peptide for use as a blocking control in assays to test for specificity of SLCO1 B1 antibody,
    Alternative Names: SLCO1B1 control peptide, SLCO1B1 antibody Blocking Peptide, Anti-SLCO1B1 Blocking Peptide, solute carrier organic anion transporter family, member 1B1 Blocking Peptide, LST-1 Blocking Peptide, MGC133282 Blocking Peptide, OATP-C Blocking Peptide, OATP1B1 Blocking Peptide, OATP2 Blocking Peptide, SLC21A6 Blocking Peptide, SLCO1B1, SLCOB-1, SLCOB 1, SLCOB-1 Blocking Peptide, SLCOB 1 Blocking Peptide
  • Application Notes

    Optimal conditions should be determined by the investigator

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Handling Advice

    Avoid repeated freeze/thaw cycles.

    Storage

    -20 °C

    Storage Comment

    Store at -20 °C long term.
  • Target

    SLCO1B1 (Solute Carrier Organic Anion Transporter Family, Member 1B1 (SLCO1B1))

    Background

    This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function.

    Molecular Weight

    76 kDa
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