4-Aminobutyrate Aminotransferase (ABAT) Peptide
ABAT
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
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- Target See all ABAT products
- ABAT (4-Aminobutyrate Aminotransferase (ABAT))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- IIVEPIQSEG GDNHASDDFF RKLRDIARKH GCAFLVDEVQ TGGGCTGKFW
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of ABAT antibody,
Alternative Names: ABAT control peptide, ABAT antibody Blocking Peptide, Anti-ABAT Blocking Peptide, 4-Aminobutyrate Aminotransferase Blocking Peptide, GABA-AT Blocking Peptide, GABAT Blocking Peptide, NPD009 Blocking Peptide
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- ABAT (4-Aminobutyrate Aminotransferase (ABAT))
- Background
- 4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50 kDa subunits complexed to pyridoxal-5-phosphate. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities.4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde.
- Molecular Weight
- 55 kDa
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