Poly (ADP-Ribose) Polymerase Family, Member 11 (PARP11) Peptide
PARP11
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN939406
Quick Overview for Poly (ADP-Ribose) Polymerase Family, Member 11 (PARP11) Peptide (ABIN939406)
Target
PARP11
(Poly (ADP-Ribose) Polymerase Family, Member 11 (PARP11))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- IKHGNTFQIH GVSLQQRHLF RTYKSMFLAR VLIGDYINGD SKYMRPPSKD
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of PARP11 antibody,
Alternative Names: PARP11 control peptide, PARP11 antibody Blocking Peptide, Anti-PARP11 Blocking Peptide, Adp-Ribose Polymerase 11 Blocking Peptide, C12orf6 Blocking Peptide, DKFZp779H0122 Blocking Peptide, Poly (ADP-ribose) polymerase 11 Blocking Peptide, PARP11, PARP-11, PARP 11, PARP-11 Blocking Peptide, PARP 11 Blocking Peptide -
Purification
- Serum
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- PARP11 (Poly (ADP-Ribose) Polymerase Family, Member 11 (PARP11))
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Background
- PARP1 encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. PARP1 can be cleaved resulting in fragements of 29 and 85 kDa.
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Molecular Weight
- 39 kDa
Target
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