Mitochondrial Ribosomal Protein L49 (MRPL49) Peptide
MRPL49
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN939455
Quick Overview for Mitochondrial Ribosomal Protein L49 (MRPL49) Peptide (ABIN939455)
Target
MRPL49
(Mitochondrial Ribosomal Protein L49 (MRPL49))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- IMVTFRNQAS RPYSFYSSLI SYEEDQRQGA EPRKNFVKPN ETKTYFWKVQ
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of MRPL49 antibody,
Alternative Names: MRPL49 control peptide, MRPL49 antibody Blocking Peptide, Anti-MRPL49 Blocking Peptide, mitochondrial ribosomal protein L49 Blocking Peptide, C11orf4 Blocking Peptide, L49mt Blocking Peptide, MGC10656 Blocking Peptide, NOF Blocking Peptide, NOF1 Blocking Peptide, MRPL49, MRPL-49, MRPL 49, MRPL-49 Blocking Peptide, MRPL 49 Blocking Peptide -
Purification
- Rabbit Anti-G3BP-1 (Ab-232) Polyclonal Antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- MRPL49 (Mitochondrial Ribosomal Protein L49 (MRPL49))
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Background
- Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. This gene and the gene for the HRD1 protein use in their respective 3' UTRs some of the same genomic sequence. Pseudogenes corresponding to this gene are found on chromosomes 5q and 8p.
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Molecular Weight
- 79 kDa
Target
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