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Actinin, alpha 2 (ACTN2) Peptide

ACTN2 Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN939512

Quick Overview for Actinin, alpha 2 (ACTN2) Peptide (ABIN939512)

Target

ACTN2 (Actinin, alpha 2 (ACTN2))

Origin

Mammalian

Source

  • 6
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Peptide Type

    Synthetic

    Sequence

    IQSYSIRISS SNPYSTVTMD ELRNKWDKVK QLVPVRDQSL QEELARQHAN

    Characteristics

    A synthetic peptide for use as a blocking control in assays to test for specificity of ACTN2 antibody,
    Alternative Names: ACTN2 control peptide, ACTN2 antibody Blocking Peptide, Anti-ACTN2 Blocking Peptide, ACTN2, ACTN-2, ACTN 2, ACTN-2 Blocking Peptide, ACTN 2 Blocking Peptide
  • Application Notes

    Optimal conditions should be determined by the investigator

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Handling Advice

    Avoid repeated freeze/thaw cycles.

    Storage

    -20 °C

    Storage Comment

    Store at -20 °C long term.
  • Target

    ACTN2 (Actinin, alpha 2 (ACTN2))

    Background

    The alpha-actinins are a multigene family of four actin-binding proteins related to dystrophin. The two skeletal muscle isoforms of alpha-actinin (ACTN2 and ACTN3) are major structural components of the Z-line involved in anchoring the actin-containing thin filaments. In humans, ACTN2 is expressed in all muscle fibres, while ACTN3 expression is restricted to a subset of type 2 fibres. Murine Actn2 and Actn3 are differentially expressed, spatially and temporally, during embryonic development and, in contrast to humans, alpha-actinin-2 expression does not completely overlap alpha-actinin-3 in postnatal skeletal muscle, suggesting independent function.

    Molecular Weight

    98 kDa
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