Actinin, alpha 2 (ACTN2) Peptide
Quick Overview for Actinin, alpha 2 (ACTN2) Peptide (ABIN939512)
Target
Origin
Source
Application
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Peptide Type
- Synthetic
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Sequence
- IQSYSIRISS SNPYSTVTMD ELRNKWDKVK QLVPVRDQSL QEELARQHAN
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of ACTN2 antibody,
Alternative Names: ACTN2 control peptide, ACTN2 antibody Blocking Peptide, Anti-ACTN2 Blocking Peptide, ACTN2, ACTN-2, ACTN 2, ACTN-2 Blocking Peptide, ACTN 2 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- ACTN2 (Actinin, alpha 2 (ACTN2))
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Background
- The alpha-actinins are a multigene family of four actin-binding proteins related to dystrophin. The two skeletal muscle isoforms of alpha-actinin (ACTN2 and ACTN3) are major structural components of the Z-line involved in anchoring the actin-containing thin filaments. In humans, ACTN2 is expressed in all muscle fibres, while ACTN3 expression is restricted to a subset of type 2 fibres. Murine Actn2 and Actn3 are differentially expressed, spatially and temporally, during embryonic development and, in contrast to humans, alpha-actinin-2 expression does not completely overlap alpha-actinin-3 in postnatal skeletal muscle, suggesting independent function.
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Molecular Weight
- 98 kDa
Target
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