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Actinin, alpha 2 (ACTN2) Peptide

ACTN2 Reactivity: Human, Mouse Host: Synthetic BP, WB
Catalog No. ABIN972865
  • Target See all ACTN2 products
    ACTN2 (Actinin, alpha 2 (ACTN2))
    Origin
    Human, Mouse
    Source
    • 6
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-ACTN2 antibody (Catalog #: ARP37422_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    ACTN2 (Actinin, alpha 2 (ACTN2))
    Synonyms
    MGC89234 Peptide, ACTN2 Peptide, 1110008F24Rik Peptide, CMD1AA Peptide, wu:fd44c03 Peptide, zgc:123223 Peptide, actinin alpha 2 Peptide, actinin, alpha 2b Peptide, actinin alpha 2 S homeolog Peptide, actn2 Peptide, ACTN2 Peptide, Actn2 Peptide, actn2b Peptide, actn2.S Peptide
    Background
    The alpha-actinins are a multigene family of four actin-binding proteins related to dystrophin. The two skeletal muscle isoforms of alpha-actinin (ACTN2 and ACTN3) are major structural components of the Z-line involved in anchoring the actin-containing thin filaments. In humans, ACTN2 is expressed in all muscle fibres, while ACTN3 expression is restricted to a subset of type 2 fibres. Murine Actn2 and Actn3 are differentially expressed, spatially and temporally, during embryonic development and, in contrast to humans, alpha-actinin-2 expression does not completely overlap alpha-actinin-3 in postnatal skeletal muscle, suggesting independent function.

    Alias Symbols: 1110008F24Rik

    Protein Interaction Partner: Myoz1,Myoz2,Myoz3,Myoz1,Myoz2,Raver1

    Protein Size: 894
    Molecular Weight
    98 kDa
    Gene ID
    11472
    NCBI Accession
    NM_033268, NP_150371
    UniProt
    Q9JI91
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