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Metalloproteinase Inhibitor 2 (TIMP2) Peptide

TIMP2 Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN939590
  • Target See all TIMP2 products
    TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))
    Peptide Type
    Synthetic
    Origin
    Mammalian
    Source
    • 10
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    IVPWDTLSTT QKKSLNHRYQ MGCECKITRC PMIPCYISSP DECLWMDWVT
    Characteristics
    A synthetic peptide for use as a blocking control in assays to test for specificity of TIMP2 antibody,
    Alternative Names: TIMP2 control peptide, TIMP2 antibody Blocking Peptide, Anti-TIMP2 Blocking Peptide, TIMP metallopeptidase inhibitor 2 Blocking Peptide, CSC-21K Blocking Peptide, TIMP2, TIMP-2, TIMP 2, TIMP-2 Blocking Peptide, TIMP 2 Blocking Peptide
  • Application Notes
    Optimal conditions should be determined by the investigator
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C long term.
  • Target
    TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))
    Synonyms
    CSC-21K Peptide, DDC8 Peptide, timp2l Peptide, zgc:65967 Peptide, zgc:85799 Peptide, D11Bwg1104e Peptide, Timp-2 Peptide, TIMP-2 Peptide, etID32613.12 Peptide, fa96h09 Peptide, timp2 Peptide, wu:fa96h09 Peptide, zgc:136726 Peptide, TIMP metallopeptidase inhibitor 2 Peptide, TIMP metallopeptidase inhibitor 2b Peptide, tissue inhibitor of metalloproteinase 2 Peptide, TIMP metallopeptidase inhibitor 2a Peptide, TIMP metallopeptidase inhibitor 2 L homeolog Peptide, TIMP2 Peptide, timp2b Peptide, Timp2 Peptide, timp2a Peptide, timp2.L Peptide
    Background
    This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.
    Molecular Weight
    22 kDa
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