Damage-Specific DNA Binding Protein 2, 48kDa (DDB2) Peptide
DDB2
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN939596
Quick Overview for Damage-Specific DNA Binding Protein 2, 48kDa (DDB2) Peptide (ABIN939596)
Target
DDB2
(Damage-Specific DNA Binding Protein 2, 48kDa (DDB2))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- IVVGRYPDPN FKSCTPYELR TIDVFDGNSG KMMCQLYDPE SSGISSLNEF
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of DDB2 antibody,
Alternative Names: DDB2 control peptide, DDB2 antibody Blocking Peptide, Anti-DDB2 Blocking Peptide, damage-specific DNA binding protein 2, 48kDa Blocking Peptide, DDBB Blocking Peptide, FLJ34321 Blocking Peptide, UV-DDB2 Blocking Peptide, DDB2, DDB-2, DDB 2, DDB-2 Blocking Peptide, DDB 2 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- DDB2 (Damage-Specific DNA Binding Protein 2, 48kDa (DDB2))
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Background
- This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities.
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Molecular Weight
- 48 kDa
Target
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