Transcription Factor MafK (MAFK) Peptide
MAFK
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN939700
Quick Overview for Transcription Factor MafK (MAFK) Peptide (ABIN939700)
Target
MAFK
(Transcription Factor MafK (MAFK))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- KEAGENAPVL SDDELVSMSV RELNQHLRGL TKEEVTRLKQ RRRTLKNRGY
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of MAFK antibody,
Alternative Names: MAFK control peptide, MAFK antibody Blocking Peptide, Anti-MAFK Blocking Peptide, v-maf musculoaponeurotic fibrosarcoma oncogene homolog K, avian Blocking Peptide, FLJ32205 Blocking Peptide, MGC71717 Blocking Peptide, NFE2U Blocking Peptide, P18 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- MAFK (Transcription Factor MafK (MAFK))
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Background
- The developmentally regulated expression of the globin genes depends on upstream regulatory elements termed locus control regions (LCRs). LCRs are associated with powerful enhancer activity that is mediated by the transcription factor NFE2. NFE2 recognition sites are also present in the gene promoters of 2 heme biosynthetic enzymes, PBGD and FECH. NFE2 DNA-binding activity consists of a heterodimer containing an 18-kD Maf protein (MafF, MafG, or MafK) and p45. Both subunits are members of the activator protein-1 superfamily of bZIP proteins. Maf homodimers suppress transcription at NFE2 sites.
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Molecular Weight
- 17 kDa
Target
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