Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 (MAPKAPK3) Peptide
MAPKAPK3
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN939713
Quick Overview for Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 (MAPKAPK3) Peptide (ABIN939713)
Target
MAPKAP Kinase 3 (MAPKAPK3)
(Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 (MAPKAPK3))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- KEEMTSALAT MRVDYDQVKI KDLKTSNNRL LNKRRKKQAG SSSASQGCNN
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of MAPKAPK3 antibody,
Alternative Names: MAPKAPK3 control peptide, MAPKAPK3 antibody Blocking Peptide, Anti-MAPKAPK3 Blocking Peptide, mitogen-activated protein kinase-activated protein kinase 3 Blocking Peptide, 3PK Blocking Peptide, MAPKAP3 Blocking Peptide, MAPKAPK3, MAPKAPK-3, MAPKAPK 3, MAPKAPK-3 Blocking Peptide, MAPKAPK 3 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- MAPKAP Kinase 3 (MAPKAPK3) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 (MAPKAPK3))
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Background
- MAPKAPK3 is a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation.
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Molecular Weight
- 43 kDa
Target
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