Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2) Peptide
EIF4G2
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN939776
Quick Overview for Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2) Peptide (ABIN939776)
Target
EIF4G2
(Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- KGFVNILMTS FLQYISSEVN PPSDETDSSS APSKEQLEQE KQLLLSFKPV
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of EIF4 G2 antibody,
Alternative Names: EIF4G2 control peptide, EIF4G2 antibody Blocking Peptide, Anti-EIF4G2 Blocking Peptide, Eukaryotic Translation Initiation Factor 4 Gamma 2 Blocking Peptide, EIF4G2, EIFG2-4, EIFG2 4, EIFG2-4 Blocking Peptide, EIFG2 4 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- EIF4G2 (Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2))
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Background
- Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. EIF4G2 shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3, eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, EIF4G2 functions as a general repressor of translation by forming translationally inactive complexes.
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Molecular Weight
- 39 kDa
Target
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