Peptidase Inhibitor 3, Skin-Derived (PI3) Peptide
PI3
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN939793
Quick Overview for Peptidase Inhibitor 3, Skin-Derived (PI3) Peptide (ABIN939793)
Target
PI3
(Peptidase Inhibitor 3, Skin-Derived (PI3))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- KGRVPFNGQD PVKGQVSVKG QDKVKAQEPV KGPVSTKPGS CPIILIRCAM
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of PI3 antibody,
Alternative Names: PI3 control peptide, PI3 antibody Blocking Peptide, Anti-PI3 Blocking Peptide, Peptidase Inhibitor 3 Skin-Derived Blocking Peptide, Skalp Blocking Peptide, ESI Blocking Peptide, MGC13613 Blocking Peptide, SKALP Blocking Peptide, WAP3 Blocking Peptide, WFDC14 Blocking Peptide, PI3, PI-3, PI 3, PI-3 Blocking Peptide, PI 3 Blocking Peptide -
Purification
- Supernatant
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- PI3 (Peptidase Inhibitor 3, Skin-Derived (PI3))
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Background
- PI3 is an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria. PI3 contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. PI3 belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines.
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Molecular Weight
- 6 kDa
Target
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