Poly(rC) Binding Protein 2 (PCBP2) Peptide
PCBP2
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN939849
Quick Overview for Poly(rC) Binding Protein 2 (PCBP2) Peptide (ABIN939849)
Target
PCBP2
(Poly(rC) Binding Protein 2 (PCBP2))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- KKGESVKKMR EESGARINIS EGNCPERIIT LAGPTNAIFK AFAMIIDKLE
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of PCBP2 antibody,
Alternative Names: PCBP2 control peptide, PCBP2 antibody Blocking Peptide, Anti-PCBP2 Blocking Peptide, Poly rC binding protein 2 Blocking Peptide, HNRPE2 Blocking Peptide, MGC110998 Blocking Peptide, hnRNP-E2 Blocking Peptide, PCBP2, PCBP-2, PCBP 2, PCBP-2 Blocking Peptide, PCBP 2 Blocking Peptide -
Purification
- Serum
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- PCBP2 (Poly(rC) Binding Protein 2 (PCBP2))
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Background
- PCBP2 appears to be multifunctional. It along with PCBP-1 and hnRNPK corresponds to the major cellular poly(rC)-binding proteins. This protein together with PCBP-1 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.
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Molecular Weight
- 39 kDa
Target
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