Ribosomal Protein S6 (RPS6) Peptide
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- Target See all RPS6 products
- RPS6 (Ribosomal Protein S6 (RPS6))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- KKNKEEAAEY AKLLAKRMKE AKEKRQEQIA KRRRLSSLRA STSKSESSQK
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of RPS6 antibody,
Alternative Names: RPS6 control peptide, RPS6 antibody Blocking Peptide, Anti-RPS6 Blocking Peptide, ribosomal protein S6 Blocking Peptide, RPS6, RPS-6, RPS 6, RPS-6 Blocking Peptide, RPS 6 Blocking Peptide
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- RPS6 (Ribosomal Protein S6 (RPS6))
- Background
- Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
- Molecular Weight
- 27 kDa
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