Aldolase B, Fructose-Bisphosphate (ALDOB) Peptide
ALDOB
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN939889
Quick Overview for Aldolase B, Fructose-Bisphosphate (ALDOB) Peptide (ABIN939889)
Target
ALDOB
(Aldolase B, Fructose-Bisphosphate (ALDOB))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- KLDQGGAPLA GTNKETTIQG LDGLSERCAQ YKKDGVDFGK WRAVLRIADQ
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of ALDOB antibody,
Alternative Names: ALDOB control peptide, ALDOB antibody Blocking Peptide, Anti-ALDOB Blocking Peptide, Aldolase B Fructose-Bisphosphate Blocking Peptide, ALDB Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- ALDOB (Aldolase B, Fructose-Bisphosphate (ALDOB))
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Background
- Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5 % of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance.
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Molecular Weight
- 39 kDa
Target
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