TRAF Family Member-Associated NFKB Activator (TANK) Peptide
TANK
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN939970
Quick Overview for TRAF Family Member-Associated NFKB Activator (TANK) Peptide (ABIN939970)
Target
TANK
(TRAF Family Member-Associated NFKB Activator (TANK))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- KPFPNQDSDS VVLSGTDSEL HIPRVCEFCQ AVFPPSITSR GDFLRHLNSH
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of TANK antibody,
Alternative Names: TANK control peptide, TANK antibody Blocking Peptide, Anti-TANK Blocking Peptide, TRAF family member-associated NFKB activator Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- TANK (TRAF Family Member-Associated NFKB Activator (TANK))
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Background
- The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. TANK is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, TANK can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation.The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily.
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Molecular Weight
- 48 kDa
Target
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