TRAF Family Member-Associated NFKB Activator (TANK) Peptide
TANK
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
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- Target See all TANK products
- TANK (TRAF Family Member-Associated NFKB Activator (TANK))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- DKNIGEQLNK AYEAFRQACM DRDSAVKELQ QKTENYEQRI REQQEQLSLQ
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of TANK antibody,
Alternative Names: TANK control peptide, TANK antibody Blocking Peptide, Anti-TANK Blocking Peptide, TRAF family member-associated NFKB activator Blocking Peptide, I-TRAF Blocking Peptide, TRAF2 Blocking Peptide
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- TANK (TRAF Family Member-Associated NFKB Activator (TANK))
- Synonyms
- I-TRAF Peptide, ITRAF Peptide, TRAF2 Peptide, C86182 Peptide, E430026L09Rik Peptide, zgc:153048 Peptide, i-traf Peptide, tank Peptide, traf2 Peptide, TRAF family member associated NFKB activator Peptide, TRAF family member-associated Nf-kappa B activator Peptide, TRAF family member-associated NFKB activator Peptide, TRAF family member associated NFKB activator L homeolog Peptide, TANK Peptide, Tank Peptide, tank Peptide, tank.L Peptide
- Background
- The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. TANK is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, TANK can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation.The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily.
- Molecular Weight
- 48 kDa
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