Mitochondrial E3 Ubiquitin Protein Ligase 1 (MUL1) Peptide
Quick Overview for Mitochondrial E3 Ubiquitin Protein Ligase 1 (MUL1) Peptide (ABIN939975)
Target
Origin
Source
Application
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Peptide Type
- Synthetic
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Sequence
- KPLDSVDLGL ETVYEKFHPS IQSFTDVIGH YISGERPKGI QETEEMLKVG
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of C1 orf166 antibody,
Alternative Names: C1ORF166 control peptide, C1ORF166 antibody Blocking Peptide, Anti-C1ORF166 Blocking Peptide, FLJ12875 Blocking Peptide, RP.2 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- MUL1 (Mitochondrial E3 Ubiquitin Protein Ligase 1 (MUL1))
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Background
- C1orf166 encodes an ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
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Molecular Weight
- 40 kDa
Target
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