A Kinase (PRKA) Anchor Protein 5 (AKAP5) Peptide
AKAP5
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN939989
Quick Overview for A Kinase (PRKA) Anchor Protein 5 (AKAP5) Peptide (ABIN939989)
Target
AKAP5
(A Kinase (PRKA) Anchor Protein 5 (AKAP5))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- KQFLISAENE QVGVFANDNG FEDRTSEQYE TLLIETASSL VKNAIQLSIE
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of AKAP5 antibody,
Alternative Names: AKAP5 control peptide, AKAP5 antibody Blocking Peptide, Anti-AKAP5 Blocking Peptide, A-kinase anchoring protein 5 Blocking Peptide, Prka Anchor Protein 5 Blocking Peptide, AKAP Blocking Peptide, AKAP75 Blocking Peptide, AKAP79 Blocking Peptide, H21 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- AKAP5 (A Kinase (PRKA) Anchor Protein 5 (AKAP5))
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Target Type
- Viral Protein
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Background
- The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. AKAP5 is a member of the AKAP family. It binds to the RII-beta regulatory subunit of PKA, and also to protein kinase C and the phosphatase calcineurin. It is predominantly expressed in cerebral cortex and may anchor the PKA protein at postsynaptic densities (PSD) and be involved in the regulation of postsynaptic events. It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT.
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Molecular Weight
- 47 kDa
Target
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