Cysteinyl-tRNA Synthetase (CARS) Peptide
Quick Overview for Cysteinyl-tRNA Synthetase (CARS) Peptide (ABIN940012)
Target
Origin
Source
Application
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Peptide Type
- Synthetic
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Sequence
- KRKKKEEAAR RKQEQEAAKL AKMKIPPSEM FLSETDKYSK FDENGLPTHD
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of CARS antibody,
Alternative Names: CARS control peptide, CARS antibody Blocking Peptide, Anti-CARS Blocking Peptide, Cysteinyl-tRNA Synthetase Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- CARS (Cysteinyl-tRNA Synthetase (CARS))
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Background
- CARS is a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer.
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Molecular Weight
- 81 kDa
Target
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