GRB2-Related Adaptor Protein (GRAP) Peptide
GRAP
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN940020
Quick Overview for GRB2-Related Adaptor Protein (GRAP) Peptide (ABIN940020)
Target
GRAP
(GRB2-Related Adaptor Protein (GRAP))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- KRQIFLRDEE PLLKSPGACF AQAQFDFSAQ DPSQLSFRRG DIIEVLERPD
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of GRAP antibody,
Alternative Names: GRAP control peptide, GRAP antibody Blocking Peptide, Anti-GRAP Blocking Peptide, Grb2-Related Adaptor Protein Blocking Peptide, MGC64880 Blocking Peptide
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GRB2-Related Adaptor Protein (GRAP) peptide
GRAP Reactivity: Human, Rat, Cow, Mouse Host: Synthetic BP, Imm
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- GRAP (GRB2-Related Adaptor Protein (GRAP))
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Background
- This gene encodes a member of the GRB2/Sem5/Drk family. This member functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain.
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Molecular Weight
- 25 kDa
Target
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