Polymerase (DNA Directed), gamma 2, Accessory Subunit (POLG2) Peptide
POLG2
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN940036
Quick Overview for Polymerase (DNA Directed), gamma 2, Accessory Subunit (POLG2) Peptide (ABIN940036)
Target
POLG2
(Polymerase (DNA Directed), gamma 2, Accessory Subunit (POLG2))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- KSHAELEGNG EHPEAPGSGE GSEALLEICQ RRHFLSGSKQ QLSRDSLLSG
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of POLG2 antibody,
Alternative Names: POLG2 control peptide, POLG2 antibody Blocking Peptide, Anti-POLG2 Blocking Peptide, polymerase, DNA directed, gamma 2, accessory subunit Blocking Peptide, HP55 Blocking Peptide, MTPOLB Blocking Peptide, PEOA4 Blocking Peptide, POLB Blocking Peptide, POLG-BETA Blocking Peptide, POLGB Blocking Peptide, POLG2, POLG-2, POLG 2, POLG-2 Blocking Peptide, POLG 2 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- POLG2 (Polymerase (DNA Directed), gamma 2, Accessory Subunit (POLG2))
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Background
- This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.
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Molecular Weight
- 53 kDa
Target
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