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Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5) Peptide

ADH5 Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN940053

Quick Overview for Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5) Peptide (ABIN940053)

Target

ADH5 (Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5))

Origin

Mammalian

Source

  • 4
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Peptide Type

    Synthetic

    Sequence

    KSVESVPKLV SEYMSKKIKV DEFVTHNLSF DEINKAFELM HSGKSIRTVV

    Characteristics

    A synthetic peptide for use as a blocking control in assays to test for specificity of ADH5 antibody,
    Alternative Names: ADH5 control peptide, ADH5 antibody Blocking Peptide, Anti-ADH5 Blocking Peptide, Alcohol Dehydrogenase 5 Blocking Peptide, ADH-3 Blocking Peptide, ADHX Blocking Peptide, FDH Blocking Peptide, Alcohol Dehydrogenase Class III chi polypeptide Blocking Peptide
  • Application Notes

    Optimal conditions should be determined by the investigator

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Handling Advice

    Avoid repeated freeze/thaw cycles.

    Storage

    -20 °C

    Storage Comment

    Store at -20 °C long term.
  • Target

    ADH5 (Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5))

    Background

    This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene.

    Molecular Weight

    40 kDa
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