Eukaryotic Translation Initiation Factor 2D (EIF2D) Peptide
Quick Overview for Eukaryotic Translation Initiation Factor 2D (EIF2D) Peptide (ABIN940111)
Target
Origin
Source
Application
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Peptide Type
- Synthetic
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Sequence
- KVTVVRNLEA YGLDPYSVAA ILQQRCQAST TVNPAPGAKD SLQVQIQGNQ
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of LGTN antibody,
Alternative Names: Ligatin control peptide, Ligatin antibody Blocking Peptide, Anti-Ligatin Blocking Peptide, HCA56 Blocking Peptide, LGTN Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- EIF2D (Eukaryotic Translation Initiation Factor 2D (EIF2D))
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Background
- LGTN is a protein receptor that localizes phosphoglycoproteins within endosomes and at the cell periphery. This trafficking receptor for phosphoglycoproteins may play a role in neuroplasticity by modulating cell-cell interactions, intracellular adhesion, and protein binding at membrane surfaces. In hippocampal neurons, long-lasting down-regulation of ligatin mRNA levels occurs via post-transcriptional RNA processing following glutamate receptor activation. This protein contains single PUA and SUI1 domains and these domains may function in RNA binding and translation initiation, respectively.
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Molecular Weight
- 65 kDa
Target
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