Crystallin, alpha B (CRYAB) Peptide
CRYAB
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN940136
Quick Overview for Crystallin, alpha B (CRYAB) Peptide (ABIN940136)
Target
CRYAB
(Crystallin, alpha B (CRYAB))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
-
-
Peptide Type
- Synthetic
-
Sequence
- KYRIPADVDP LTITSSLSSD GVLTVNGPRK QVSGPERTIP ITREEKPAVT
-
Characteristics
-
A synthetic peptide for use as a blocking control in assays to test for specificity of CRYAB antibody,
Alternative Names: Crystallin Alpha B control peptide, Crystallin Alpha B antibody Blocking Peptide, Anti-Crystallin Alpha B Blocking Peptide, CRYAB Blocking Peptide, CRYA2 Blocking Peptide, CTPP2 Blocking Peptide, HSPB5 Blocking Peptide
-
-
Crystallin, alpha B (CRYAB) peptide
CRYAB Reactivity: Human, Mouse, Rat Host: Synthetic BP, Imm
-
-
Application Notes
- Optimal conditions should be determined by the investigator
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
-
Buffer
- PBS
-
Handling Advice
- Avoid repeated freeze/thaw cycles.
-
Storage
- -20 °C
-
Storage Comment
- Store at -20 °C long term.
-
-
- CRYAB (Crystallin, alpha B (CRYAB))
-
Background
- Alpha crystallins are composed of: alpha-A and alpha-B, for acidic and basic, respectively. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone, instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. Alpha-A and alpha-B are differentially expressed, alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Elevated expression of alpha-B crystallin occurs in many neurological diseases, a missense mutation cosegregated in a family with a desmin-related myopathy.
-
Molecular Weight
- 12 kDa
Target
-
You are here:
