Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) Peptide
RASSF1
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN940157
Quick Overview for Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) Peptide (ABIN940157)
Target
RASSF1
(Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- LAGPSDKALS FVLKENDSGE VNWDAFSMPE LHNFLRILQR EEEEHLRQIL
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of RASSF1 antibody,
Alternative Names: RASSF1 control peptide, RASSF1 antibody Blocking Peptide, Anti-RASSF1 Blocking Peptide, Ras association, RalGDS/AF-6 domain family member 1 Blocking Peptide, 123F2 Blocking Peptide, NORE2A Blocking Peptide, RASSF1A Blocking Peptide, RDA32 Blocking Peptide, REH3P21 Blocking Peptide, RASSF1, RASSF-1, RASSF 1, RASSF-1 Blocking Peptide, RASSF 1 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))
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Background
- This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Seven alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
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Molecular Weight
- 30 kDa
Target
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