Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) Peptide
SUV39H2
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN940256
Quick Overview for Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) Peptide (ABIN940256)
Target
SUV39H2
(Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- LDTRLPRIAL FSTRTINAGE ELTFDYQMKG SGDISSDSID HSPAKKRVRT
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of SUV39 H2 antibody,
Alternative Names: SUV39H2 control peptide, SUV39H2 antibody Blocking Peptide, Anti-SUV39H2 Blocking Peptide, Suppressor Of Variegation 3-9 Homolog 2 Blocking Peptide, FLJ23414 Blocking Peptide, KMT1B Blocking Peptide, SUV39H2, SUVH2-39, SUVH2 39, SUVH2-39 Blocking Peptide, SUVH2 39 Blocking Peptide
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Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) peptide
SUV39H2 Reactivity: Human, Pig, Cow, Dog, Mouse, Rat Host: Synthetic BP, Imm
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- SUV39H2 (Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2))
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Background
- SUV39H2 is a histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 'Lys-9' trimethylation is also required to direct DNA methylation at pericentric repeats.
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Molecular Weight
- 40 kDa
Target
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