Aldo-keto Reductase Family 1, Member C2 (AKR1C2) Peptide
Quick Overview for Aldo-keto Reductase Family 1, Member C2 (AKR1C2) Peptide (ABIN940266)
Target
Origin
Source
Application
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Peptide Type
- Synthetic
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Sequence
- LEAVKLAIEA GFHHIDSAHV YNNEEQVGLA IRSKIADGSV KREDIFYTSK
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of AKR1 C2 antibody,
Alternative Names: AKR1C2 control peptide, AKR1C2 antibody Blocking Peptide, Anti-AKR1C2 Blocking Peptide, Aldo-Keto Reductase Family 1 Member C2 Blocking Peptide, Dihydrodiol Dehydrogenase 2 Blocking Peptide, Bile Acid Binding protein Blocking Peptide, 3-alpha hydroxysteroid dehydrogenase type III Blocking Peptide, AKR1C-pseudo Blocking Peptide, BABP Blocking Peptide, DD Blocking Peptide, DD2 Blocking Peptide, DDH2 Blocking Peptide, HAKRD Blocking Peptide, HBAB Blocking Peptide, MCDR2 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))
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Background
- This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
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Molecular Weight
- 37 kDa
Target
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